For major requirements, see the School of Allied Health section of this Catalog.
222. Medical Cytogenetics
(Formerly offered as MLS 205.) Both semesters. Four credits. Two 2-hour lectures. Prerequisite: MCB 203; MCB 200 or 213; all of which may be concurrent. Open to students in the Diagnostic Genetic Sciences Program; others who have met the prerequisites.
Birth defects, prenatal assessment, cell culture and harvest, staining and banding techniques, mechanisms of numerical and structural chromosome abnormality, numerical syndromes, duplication and deletion syndromes, the sex chromosomes, sex chromosome abnormalities, human chromosome nomenclature, mosaicism, genetic imprinting, cancer cytogenetics, molecular cytogenetic testing.
223. Laboratory in Cytogenetics
(Formerly MLS 203.) Both semesters. Three credits. One 3-hour laboratory period and 1-hour discussion. Four additional laboratory sessions are required during the first half of the semester. Prerequisite: DGS 222 (Formerly MLS 205.) which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of instructor.
Human chromosome morphology and identification, aseptic technique, lymphocyte culture and harvest, chromosome banding, karotyping and microscopic analysis of normal and abnormal cases.
234. Diagnostic Molecular Technologies
(Formerly MLS 217.) Both semesters. Three credits. Prerequisite: MCB 200 or 213; and MLS 208 or MCB 211 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with instructor consent.
DNA and RNA diagnostic technologies used in
clinical settings; clinical applications in prenatal diagnosis; cancer
management, transplantation, paternity testing, forensic medicine and microbiology.
235. Laboratory in Molecular Diagnostics
Both semesters. Four credits. Prerequisite: MLS 234 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others by consent of instructor.
DNA isolation, blotting techniques, fluorescent in situ hybridization, polymerase chain reaction and Genprobe assay.
242. Chromosome Imaging
First semester and Summer Session I. Two credits. Two hours of lecture and 1 hour of discussion. Prerequisites: DGS 222 and 223. Open only to DGS majors; others with consent of instructor. Fall offering open only to DGS students with a Spring Clinical.
Theory and techniques of bright field microscopy, black and white film processing and printing, and computerized imaging for karyotype production.
246. Contemporary Issues in Human Genetics
Both semesters. Three credits. Prerequisite: DGS 223 (Formerly MLS 203) and DGS 222 (Formerly MLS 205). Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of the instructor.
Advanced karotyping and microscopic diagnosis; report writing; historical perspective; recent advances and future trends in human genetics; ethical issues of genetic research, technological advances, genetic diagnosis and the practice of medical genetics; exploration of the lay person's understanding of human genetics and genetic diagnosis.
260. Blotting Methods
Both semesters. Six credits. Prerequisite: DGS 234 and 235. Open only to DGS molecular certificate students.
Practicum experience with blotting technologies stressing complete Southern analysis.
261. Amplification Methods
Both semesters. Six credits. Prerequisite: DGS 234 and 235. Open only to DGS molecular certificate students.
Practicum experience in DNA and/or RNA amplification stressing polymerase chain reaction.
273. Research in Molecular Genetics
Both semesters. One credit. Prerequisites: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.
Design and implementation of a research project in molecular genetics.
275. In Situ Hybridization Methods
Both semesters. Two credits. Prerequisites: DGS 234 and 235. Open only to DGS molecular certificate students.
Practicum in fluorescence in situ hybridization or other in situ hybridization techniques.
276. Topics in Molecular Genetics
Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.
Exploration of an individual area of interest in molecular genetics.
277. Mutagenesis
Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.
Practicum experience in mutagenesis, including Ames assays and mammalian mutagenesis assays.
278. DNA Sequencing
Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.
Practicum experience in DNA sequencing.
279. Microbiological Applications of Regular Diagnostics
Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.
Practicum experience in the application of molecular technologies to microbiology.
280. Bone Marrow Cytogenetics
(Formerly MLS 271.) Both semesters. Two credits. Prerequisite: In order to enroll in the course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205) and DGS 223 (Formerly MLS 203). Open only to Diagnostic Genetic Sciences majors. Clinical Staff
Culture, harvest, banding and analysis of leukemic bone marrow samples; chromosomal abnormalities associated with hematologic malignancies.
281. Peripheral Blood Cytogenetics
(Formerly MLS 271.) Both semesters. Four credits. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205) and DGS 223 (Formerly MLS 203). Open only to Diagnostic Genetic Sciences majors. Clinical Staff
Culture, harvest, banding and analysis of peripheral blood samples.
282. Practicum in Staining and Karyotyping
(Formerly MLS 272.) Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205) and DGS 223 (Formerly MLS 203). Open only to Diagnostic Genetic Sciences majors. Clinical Staff
Utilization and application of special staining and banding techniques, karotyping of normal and abnormal metaphases from all specimen types.
283. Practicum in Photomicroscopy/Imaging
(Formerly MLS 273.) Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205), DGS 223 (Formerly MLS 203), and DGS 242. Open only to Diagnostic Genetic Sciences majors. Clinical Staff
Techniques of photomicroscopy, B/W film development, print enlargement, computer imaging.
284. Variable Topics in Cytogenetics
(Formerly MLS 275.) Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205) and DGS 223 (Formerly MLS 203). Open only to Diagnostic Genetic Sciences majors. Clinical Staff
In-depth examination of a topic of the students' choosing in the field of human genetics.
285. Research in Cytogenetics
(Formerly MLS 276.) Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205) and DGS 223 (Formerly MLS 203). Open only to Diagnostic Genetic Sciences majors. Clinical Staff
Design and implementation of a research project in clinical cytogenetics.
286. Prenatal Cytogenetics
(Formerly MLS 277.) Both semesters. Four credits. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 (Formerly MLS 205) and DGS 223 (Formerly MLS 203). Open only to Diagnostic Genetic Sciences majors. Clinical Staff
Culture, harvest, banding and analysis of amniotic fluids, products of conception, and other fetal samples.
298. Special Topics
Either semester. Credits and hours by arrangement. Prerequisite: The completion of all Lower Division requirements in the Diagnostic Genetic Sciences Program. Open only with consent of instructor. May be repeated for credit.
Application of the scientific method of inquiry to planning, implementation, evaluating and reporting a study of a problem in cytogenetics.
299. Independent Study for Undergraduates
Either semester. Credits and hours by arrangement. Open only with consent of instructor. May be repeated for credit.
This course is designed primarily for students who wish to extend their knowledge in some specialized area in the field of diagnostic genetic sciences.